If you are experiencing menopause hair loss – there is a new player on the market. Nanoxidil.

You have probably heard of Rogaine which contains Minoxidil. A new product by DS Laboratories contains Nanoxidil. Nanoxidil has a similar chemical structure to Minoxidil but is less irritating to the scalp.

Does Nanoxidil actually work?

What studies have been done?

How long does it take to see results?

Why choose Nanoxidil over Minoxidil (Rogaine)?

Is it going to work for menopause hair loss?

Flo Hive has done the hard yards to answer all these questions. Let’s do this!

Key Takeaways

Nanoxidil was formulated to reduce the scalp irritation some customers were experiencing with Rogaine.

Nanoxidil has been studied – but it has not been on the market for as long as Minoxidil. Therefore less studies have been done.

Nanoxidil works by blocking the androgen DHT. In the study we reviewed 47% of participants saw results in just 3 months, 96% of participants had results in 6 months.

The formula Flo Hive likes includes other ingredients that suppress DHT and prevent hair shedding as well (azelaic acid and caffeine).

Jump to Flo Hive pick HERE.

Understanding menopause hair loss

Hair loss in menopause can be caused by the drop is in estrogen and progesterone. Both hormones protect against another hormone you already have in your body which is androgen DHT (dihydrotestosterone).

DHT encourages hair loss on the head. As DHT rises slightly in menopause combined with the big drop in estrogen and progesterone means DHT becomes more potent. It really goes to town, encouraging your hair to fall out!

There can be other causes of hair loss, so it is essential to go to your doctor to rule out anything else. Other causes can be thyroid conditions, vitamin and mineral deficiencies (zinc, iron) to name a few.

Best to make sure there are no other underlying causes. If there are none, then the hair loss is most likely being caused by the drop in estrogen and progesterone.

Sometimes using hormone therapy (MHT) can be enough to rectify hair loss. Or you may need to pursue hair regrowth treatments to work in conjunction with MHT to restore your hair density.

What is Nanoxidil?

As we said – the cause of menopause hair loss is invariably due to the drop in estrogen and progesterone allowing DHT to become more potent. DHT makes the hair on your head fall out. This is where DHT blockers come in. DHT blockers work locally on the scalp to supress DHT, and therefore – you can regrow your hair.

It really is that straightforward!

If you were to see a dermatologist for menopause hair loss they may suggest medications. Minoxidil is one such medication for hair loss. Minoxidil also comes in a topical serum – Rogaine – which you can apply directly to the scalp.

Nanoxidil is the close cousin of Minoxidil. Nanoxidil was formulated to address the issues some people experience with irritation on the scalp from Minoxidil. Minoxidil works to regrow hair through vasodilation. Whereas Nanoxidil regrows hair by blocking DHT.

Flo Hive Science Scoop

Nanoxidil has been studied. But since Minoxidil has been on the market much longer, it has a lot more research behind it.

Whilst several studies stand out, the one with the most female participants and over the longest period of time (what Flo Hive is always on the look out for!) is this study. The study included only women with an average age of 45.

Participants used a spray called Spectral. DNC-N (by DS Laboratories) twice a day. Their hair shedding and hair density were assessed. First at 3 months and then assessed again, at 6 months.

The formula contained multiple ingredients to suppress DHT and encourage hair growth including – Nanoxidil, azelaic acid, adenosine, retinol, and caffeine.

At month 3 – 47% of participants had moderately or greatly increased hair density due to decreased shedding. After 6 months of treatment 96% of participants had an improvement in hair mass density. After 6 months the results remained stable.

The study included photographic evidence. Pictures are below:

DS Laboratories Spectral.DNC-N Hair Growth Serum - Hair Thickening Products for Women & Men, Hair Regrowth Serum, Hair Growth Products for Hair Loss & Thinning Hair, Hair Serum for Hair Growth

Minoxidil VS Nanoxidil

The main difference is irritation to the scalp. Nanoxidil is less likely to cause irritation. It’s the reason it was created – to address that issue.

The two brands we are comparing are Rogaine and DS Laboratories:

FeatureRogaine For WomenDS Laboratories Spectral.DNC-N
Active ingredientsMinoxidil 5%Nanoxidil 5%, azelaic acid*, adenosine** and caffeine***
DHT Blocking Side EffectsNoYes
Application MethodTopicalTopical
FDA Approval YesNo
Clinical ResultsExtensiveLimited
Suitable for Sensitive ScalpsNoYes
Usage FrequencyOnce dailyTwice daily

*Azelaic acid – a small study on men with androgenic alopecia experienced regrowth using azelaic acid. Click here for study.

**Adenosine – has been shown to reduce hair shedding. Click here for study.

***Caffeine – has been extensively proven to prevent hair shedding. You can read our science review of caffeine here.

Where to buy Nanoxidil

To replicate the scientific study we reviewed at home, you would use Spectral DNC-N by DS Laboratories.

We recommend products and services based on their research backing, as determined by a review of clinical studies. We receive compensation when readers purchase the products or services we recommend.

Conclusion – will it work for menopause?

Yes it could definitely work – provided the cause of your hair loss is due to DHT making your hair fall out. The best thing to do (if you haven’t already) is check with your doctor to rule out any other potential causes. Then you will know that it is your drop in female sex hormones that is the cause.

This happened to the Editor of Flo Hive recently. All bloodwork came back fine for Vitamin D, Zinc, Iron, thyroid etc. Therefore, the natural conclusion to draw is – the drop in hormones is the cause of her hair loss.

Flo Hive is liking this formula over traditional Rogaine. Because it includes other hair growth ingredients – such as azelic acid. Plus it has caffeine to prevent hair shedding. Thus making it a much more well rounded formula offering additional benefits.

DS Laboratories Spectral.DNC-N Hair Growth Serum - Hair Thickening Products for Women & Men, Hair Regrowth Serum, Hair Growth Products for Hair Loss & Thinning Hair, Hair Serum for Hair Growth

Exactly how much of each ingredient is present in the formula is unknown, but we think these extra ingredients coupled with the low-irritant formulae make it a superior choice to Rogaine.

The short regrowth timeframe is also appealing. Getting results in three months is very impressive. Nanoxidil has been studied, but not as thoroughly as Minoxidil. If you prefer to try a formulae with a longer history of data – you may want to opt for Rogaine.

If you have a sensitive scalp and would like to try a formulae with less irritants then Flo Hive suggests using Spectral DNC-N

We recommend products and services based on their research backing, as determined by a review of clinical studies. We receive compensation when readers purchase the products or services we recommend.

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7861115

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419033

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457957

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489052

https://pubmed.ncbi.nlm.nih.gov/16343028/

https://pubmed.ncbi.nlm.nih.gov/35408582/

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